And what if, depending on the age at which it develops, hypertension had more or less significant consequences on maintaining our cognitive function? This was suggested by a study conducted by an Inserm team in partnership with the Department of Epidemiology and Public Health at University College London which has been monitoring changes in blood pressure and the onset of dementia in more than 10,000 volunteers since 1985. This...
Will the radiology of the future come from machine learning? That is the view of Inserm and Inria researchers working in collaboration at the Université Grenoble Alpes who have developed a program able to localize and diagnose various types of brain tumors via MRI image analysis. These analyses have produced highly reliable results, with tumor localizations and tumor-type diagnoses accurate in 100% and over 90% of cases, respectively. This...
Do you tend to go for cake or vegetables? If you sometimes find it difficult to eat healthily, a study conducted by a team of researchers from Inserm, CNRS and Sorbonne Université, including Liane Schmidt and Hilke Plassmann, at the Brain & Spine Institute (ICM) has established a link between the anatomy of certain regions of our brain and our ability to control our food choices. These results were...
Des chercheurs de l’Inserm et de l’Université de Lille, ont découvert que le plus fréquent des troubles de la fertilité féminine - le syndrome des ovaires polykystiques (SOPK) - serait causé par la surexcitation de neurones cérébraux. La coupable : une hormone produite par les ovaires, appelée « Hormone anti-müllerienne» (AMH), suproduite chez les femmes souffrant d’un SOPK. Les travaux de l’équipe chez la souris montrent l’importance de l’exposition in...
Living beings are able to integrate and identify relevant sensory information, such as smells, sounds or light, in order to regulate how they behave in the presence of potential danger. This is called context discrimination. Inserm researchers based at Neurocentre Magendie in Bordeaux have recently discovered which neurons are implicated in this phenomenon and where they are located. Good news for sufferers of post-traumatic stress disorder in whom context...
Des chercheurs ont mis en évidence le mécanisme responsable de l'installation et du maintien de la douleur chronique et proposent un prototype de traitement innovant avec un effet thérapeutique immédiat et durable.
Drug addiction behaviors and vulnerability to relapse are linked to our brain’s ability to produce new neurons. This is the finding of Inserm researchers from Neurocentre Magendie at the University of Bordeaux, after observing the behavior of mice taught to self-administer cocaine. Their results, to be published in Molecular Psychiatry, show a link between the deficient production of new neurons in the hippocampus and addiction to drugs.
The INSIGHT-preAD study, directed by Prof. Bruno Dubois, is being carried out by teams from Inserm, CNRS and Université Sorbonne at the Brain and Spine Institute (ICM) and the Memory and Alzheimer’s Disease Institute (IM2A) at AP-HP Pitié-Salpêtrière Hospital in Paris, in collaboration with the MEMENTO cohort. It aims at identifying factors underlying Alzheimer’s disease development in healthy subjects over 70 with no existing cognitive disorders. Sponsored by...
A team of Inserm researchers led by Howard Cooper (Inserm Unit 1208 "Stem Cell and Brain Institute") in collaboration with their colleagues in the U.S. have for the first time established a reference map of gene expression, by organ and time of day. A mammoth task that began a decade ago and has required two years of analysis. These results, published in Science, show just how important it is...
Could we have been wrong over the past 70 years in thinking that certain regions of the brain are insensitive to pain? This is what the findings of a team of researchers from Inserm, Nice University Hospital, Université Côte d’Azur and St Anne Hospital in Paris would suggest. By collecting observations of brief painful events occurring during brain surgery in awake patients, they found that certain structures – hitherto...