Researchers have shown that a commercially-available vaccine can overcome resistance to immunotherapy. Their study, published in Science Translational Medicine, shows that not only can gastroenteritis vaccines induce the immunogenic death of cancer cells in vitro, but also that combining them with immunotherapy triggers a potent anti-tumor immune response in vivo – where immunotherapy alone had failed.
Physical activity is thought to be our greatest ally in the fight against cardiovascular disease. But there may be significant variations in its protective effects across a range of different situations, such as regularly playing a sport, carrying heavy loads at work, or going for a walk with friends. These are the findings of a new study led by Inserm researcher Jean-Philippe Empana (U970 PARCC, Inserm/Université de Paris) in...
Teams of the Clinical Research Unit in Health Economics "ECO Île-de-France" * at the Hotel Dieu AP-HP, the Clinical Epidemiology Unit and Pediatric Endocrinology-diabetology Service hospital Robert Debré AP-HP, and mixed research unit INSERM / University of Paris U1123 "clinical Epidemiology and economic evaluation applied to vulnerable populations (ECEVE) conducted a study on the association between job insecurity, duration of hospital stay and hospital costs in pediatrics. More than...
Acute myeloid leukemia (AML) mainly affects children, with the prognosis often being poor despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children.
Most of our choices are not motivated by curiosity but by errors caused by the brain mechanisms implicated in evaluating our options.
One hypothesis put forward to explain the repetitive behaviors of people with Autism Spectrum Disorder is a lack of cognitive flexibility. However, this may well not be the case. A recent study used MRI to track the brain activity of autistic and non-autistic subjects faced with situations similar to those that cause problems in the daily lives of people with the disorder. Their findings, published in Brain and Cognition,...
Rare diseases represent a global problem. Until now, the lack of data made it difficult to estimate their prevalence. Created and coordinated by Inserm, the Orphanet database, has made it possible to obtain a global estimate.
A joint study led by several teams open skin regeneration medecine to new insights.
Although persistent organic pollutants (POPs) are already suspected to promote breast cancer, there has been little research into how they affect its aggressiveness.
Scientists have shown that delta waves emitted while we sleep are not generalized periods of silence during which the cortex rests, as has been described for decades in the scientific literature. Instead, they isolate assemblies of neurons that play an essential role in long-term memory formation.
