Une équipe de chercheurs est parvenue à estimer le nombre de nouveaux cas et le coût économique direct que représentent les infections à bactéries résistantes aux antibiotiques chez les malades hospitalisés, pendant les années 2015 et 2016.
Firibastat is the first in a new class of antihypertensive drugs targeting the renin-angiotensin system in the brain.
ChroMS is a new microscopy technique bringing together color, 3D and high-resolution imaging, and is nothing short of a revolution in vertebrate brain imaging.
The team of Béhazine Combadière, Inserm Research Director at Unit 1135 "Center for Immunology and Infectious Diseases", has been working for years on the impact of vaccine administration routes on the quality of immune responses.
Cesarean delivery is thought to be linked to a greater risk of severe maternal complications – primarily hemorrhagic - than vaginal delivery, especially in women aged 35 and over.
How can the quality of life of patients with narcolepsy, the severest sleep disorder in humans, be improved? An international scientific team led by Yves Dauvilliers, a researcher at Inserm and Université de Montpellier, is working on Solriamfetol – a promising new drug that stimulates alertness and improves resistance to sleepiness.
Researchers are now able to edit the genome with precision using the "gene editing scissors" of CRISPR-Cas9, which is a highly promising tool for gene therapy. The technical challenge now is to get this tool into the genome of certain cells. With this in mind, a joint team from Inserm, the CNRS, the Université Claude Bernard Lyon 1, and the École Normale Supérieure de Lyon, working within the International...
1.2 million people in the world are co-infected by Mycobacterium tuberculosis, the bacteria which causes tuberculosis, and AIDS (HIV-1). This combination is deadly: it makes patient diagnosis and treatment difficult, and increases the pathogenicity of these two infectious agents. An international team led by researchers at the CNRS and Inserm have revealed that in the presence of tuberculosis, HIV-1 moves from one cell to the next via nanotubes which...
Inserm and CNRS researchers from the Institute of Genetics and Molecular and Cellular Biology (Inserm/CNRS/Université de Strasbourg) have discovered how myotubularin - a protein deficient in myotubular myopathy - interacts with amphiphysin 2 and suggest targeting the latter in order to treat patients.
Les microbes colonisent l’ensemble des surfaces de notre corps et participent au bon équilibre de notre système immunitaire. Chez les nouveau-nés, le microbiote intestinal est d’abord formaté par les composants du lait maternel. Lors de la diversification alimentaire, il se développe et de nombreuses bactéries prolifèrent. Des chercheurs de l’Institut Pasteur et de l’Inserm montrent chez la souris qu’une réponse immunitaire importante se produit lors de l’introduction de nourriture...