Could a common mushroom help fight certain genetic diseases? Although surprising, this is indeed the new discovery made by French scientists from Inserm, the French National Museum of Natural History, the CNRS, Université de Lille, and the Institut Pasteur de Lille[1]. By examining numerous extracts, the scientists thus evidenced that the mushroom, Lepista inversa, acted significantly on three isolated cell lines taken from patients with cystic fibrosis. This research...
The “Nuclear Domains and Pathologies” team led by Jean-Jacques Diaz, Inserm Research Director at the Cancer Research Center of Lyon (Inserm/CNRS/Université Claude Bernard Lyon 1/Centre Léon Bérard), has recently demonstrated that one of the essential components of the "cellular machinery" that produces proteins – the ribosome – is altered in tumors. The researchers have observed that these modified ribosomes function differently in cancer cells, preferentially producing proteins that favor...
A new study by Olivier Tabary and his colleagues at the Saint-Antoine Research Center (Inserm Unit 938/Université Pierre et Marie Curie (UPMC), Sorbonne Universities) has revealed a new mechanism that makes it possible to restore the functioning of a cell channel found particularly in the lung mucosa of cystic fibrosis patients. This transfer, usually operated by the CFTR protein, is deficient in patients with cystic fibrosis and known for...
After 40 years of research, researchers at the CEA, the CNRS, the University of Grenoble-Alps, the University of Montpellier and the Inserm have finally identified the enzyme responsible for the tubulin cycle. Surprisingly, it is not one enzyme but two which control the cycle of this essential component of the cytoskeletal structure. This work opens up new prospects for the improved understanding of the role of tubulin, changes in...
Introduced by the World Health Organization in 1988 and observed in many countries each year since, this day aims to inform and raise awareness of the prevention, treatment and management of human immunodeficiency virus (HIV)/AIDS.
A lower risk of type 2 diabetes has been observed among individuals consuming food rich in antioxidants. This effect is largely contributed by fruit, vegetables, tea and other hot beverages, as well as moderate consumption of alcohol, as shown in a recent study from an Inserm research group, published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD)
A study coordinated by Dr. Boris Hansel and Prof. Ronan Roussel, from the Diabetes-Endocrinology and Nutrition Department at Hôpital Bichat – Claude-Bernard, AP-HP and the Cordeliers Research Center (Inserm/Pierre and Marie Curie University, Paris Diderot, Paris Descartes University) shows that online nutritional coaching -an automated nutritional support program- improves dietary habits and glycemic control in patients with type 2 diabetes and abdominal obesity.
Celebrated every November 14 since its creation in 1991, World Diabetes Day is an opportunity to raise collective awareness of the condition and, above all, the resources deployed to manage it. Diabetes refers to consistently higher than normal blood sugar levels (hyperglycemia).
The intestinal microbiota still has surprises in store. The mode of action of a probiotic bacteria used in the symptomatic treatment of pain in irritable bowel syndrome has been revealed in a new study conducted by scientists from Inserm, Université de Toulouse and CHU de Toulouse [1] within the Digestive Health Research Institute (Inserm/INRA/Université Toulouse III – Paul Sabatier, ENVT). The bacteria produces a neurotransmitter (GABA) which, when bound to...
Une étude publiée dans la revue Science démontre que la prise d’antibiotiques affecte l’efficacité d’un traitement par immunothérapie chez des patients atteints d’un cancer.