A study conducted on mice by researchers at Inserm and UPMC (Pierre and Marie Curie University) offers a new type of immunotherapy approach for treating Alzheimer's disease. This involves amplifying a specific population of T lymphocytes that regulate immune and neuroinflammatory mechanisms that develop during the disease.These results are published in the journal Brain.
Researchers from the Institut Pasteur, Inserm, CNRS and Paris Descartes – Sorbonne Paris Cité University recently published a large-scale study in Nature Genetics based on almost 7,000 strains of Listeria monocytogenes — the bacterium responsible for human listeriosis, a severe foodborne infection. Through the integrative analysis of epidemiological, clinical and microbiological data, the researchers have revealed the highly diverse pathogenicity of isolates belonging to this bacterial species.Comparative genomics led...
12 patients suffering from severe erectile dysfunction following prostate cancer received a transplant of stem cells into the penis. After six months, significant improvements in the quality of sexual intercourse, erection, penile rigidity and quality of orgasm were reported by the patients, according to a study by Inserm. This clinical trial was conducted under the direction of Professor René Yiou at the Department of Urology, Henri Mondor University Hospital,...
The European Commission has granted over 22 million Euros to the European HIV Vaccine Alliance (EHVA) to develop a multidisciplinary platform to evaluate novel preventive and therapeutic vaccines.
Researchers at Inserm Unit 1194, “Montpellier Cancer Research Institute” (Inserm/University of Montpellier/Montpellier Regional Cancer Institute) have confirmed the value of a new test to identify cancer patients who will be free of sequelae following radiotherapy. This test, conducted on a blood sample taken from 500 breast cancer patients, treated in 10 centres in France, and monitored for 3 years, showed that women with a high rate of radiation-induced lymphocyte...
Initiated by ECCA (European Cervical Cancer Association), this campaign, which will run from 24 to 30 January next, is aimed at raising awareness among the general public and health professionals about cervical cancer prevention and screening.
Faecalibacterium prausnitzii is an intestinal bacterium that is abundant in healthy adults but scarce in those suffering from inflammatory bowel disease. Using a mouse model, a team of scientists from INRA, INSERM, and the University of Auvergne has discovered that the bacterium possesses analgesic properties, a finding just published in Scientific Reports (January 18, 2016).Given that F. prausnitzii also exhibits anti-inflammatory effects, the bacterium shows great promise as a...
And if a simple oxygen mask were to protect people from neurological sequelae following an acute stroke? It would be sufficient to administer it to patients during the interval needed by medical teams to restore the blood supply, and hence oxygen, to the brain. At any rate, this is the hypothesis formulated by Jean-Claude Baron, Inserm Research Director at Unit 894, “Psychiatry and Neurosciences Research Center,” in collaboration with...
Over half of the patients who die suddenly have early warning signs, allowing ample time for intervention, according to an Inserm study conducted by Eloi Marijon, a researcher and cardiologist at the Paris Cardiovascular Research Center (Inserm Unit 970 / George Pompidou European Hospital, AP-HP) This work is published in the journal Annals of Internal Medicine.
Interest in the intestinal microbiota, or intestinal flora, has grown considerably in recent years. In 2015, over 4,500 scientific studies on the subject were published in PubMed.
The first embryonic division, which follows gamete fusion (oocyte and spermatozoon), starts the development of a new individual, the genesis of a functional adult body. This division is symmetric in the one-cell embryo stage (also known as the zygote); it leads to the formation of two daughter cells of identical size. Conversely, it is asymmetric in the oocyte, which has the same size and shape as the zygote. Why?...
