Matteo Serino, chargé de recherche Inserm à l’Institut de recherche en santé digestive (IRSD, une unité mixte de recherche Inserm/Université Toulouse III- Paul Sabatier/Ecole nationale vétérinaire de Toulouse/Inra), et ses collaborateurs, montrent que l’altération du microbiote intestinal, qu’elle soit d’origine nutritionnelle ou génétique, peut avoir des effets bénéfiques sur le métabolisme du foie. Ces résultats contredisent des résultats précédents obtenus dans le domaine qui montraient que le transfert d’un...
French researchers have identified a marker that makes it possible to differentiate “dormant” HIV-infected cells from healthy cells. This discovery will make it possible to isolate and analyze reservoir cells which, by silently hosting the virus, are responsible for its persistence even among patients receiving antiviral treatment, whose viral load is undetectable. It offers new therapeutic strategies for targeting infected cells. This research is part of the ANRS strategic...
Researchers at the French National Institute for Agricultural Research (Inra) and Inserm have discovered a new family of bacterial enzymes that can produce hitherto unidentified peptides with antibiotic activity. Published in Nature Chemistry, this work holds promise for the synthesis of molecules of pharmaceutical interest and the design of new antibiotics.
A new study conducted by Inserm researchers at Irset (Institute of Research in Environmental and Occupational Health)[1] shows that ibuprofen is liable to cause disruptions in the hormone system in the human foetal testis, with possible implications for the development of the male urogenital tract. This drug suppresses the production of various testicular hormones, including testosterone, which controls the primary and secondary sex characteristics and the descent of the...
La 19ème édition de la Semaine du Cerveau, coordonnée par la Société des Neurosciences, se déroulera du 13 au 19 mars 2018, en France et dans 62 autres pays. Lors des nombreuses manifestations, le grand public est invité à aller à la rencontre des chercheurs pour mieux comprendre le fonctionnement du cerveau et s’informer sur les dernières avancées de la recherche.
Postural instability is the main factor associated with falls in patients with Parkinson disease, but there are other symptoms, such eye disorders. Teams from Pitié-Salpêtrière Hospital, AP-HP, and the Brain and Spine Institute (Inserm, CNRS, UPMC) have examined the link between these eye disorders observed in some patients and postural instability. Their results demonstrate a potential new marker of posture control in Parkinson disease. These results are published in...
Not sleeping enough or going to bed too late leads to a reduction in the volume of grey matter in the brains of adolescents. These conclusions were obtained by researchers at Inserm Unit 1000, “Neuroimaging and Psychiatry” (Inserm/Paris-Descartes University/Paris Sud University), who studied the brain and sleep habits of 177 14-year-old students. This work is published in the journal Scientific Reports, and received support from the Academy of Finland.
In 2014, Inserm established a think-tank on “Gender and Health Research” within the Inserm Ethics Committee. Led by Catherine Vidal and Jennifer Merchant, members of the Inserm Ethics Committee, its objectives are to raise awareness about the impact of gender on health research, and to conduct an ethical reflection on the gender dimension, which is often overlooked in biomedical research.
L’Inserm se classe 9e dans le « Top 25 Global Innovators - Government » Reuters/Clarivate, qui évalue la capacité d’innovation des organisations publiques en fonction de l’impact de leur production scientifique et de leurs brevets.
Some cancer cells are resistant to treatment and persist. If they are capable of proliferating again, even a very small number of these cells may be enough to reconstitute a tumour after or despite treatment. Various approaches to eliminate these “cancer stem cells” (CSCs) have been tried in recent years: targeted therapies, vaccination and tumour starvation. In an article published in the journal Cell Reports, Christophe Ginestier, Inserm Research...
Wednesday 1 March 2017 will see the unveiling of the interministerial plan for “mobilisation and action on violence against children” by Laurence Rossignol, Minister for Families, Children and Women’s Rights.
