Researchers at Unit 1018 “Centre for Research in Epidemiology and Population Health” (Inserm/Paris-Sud University) at Gustave Roussy have focused on the proportion of breast cancers attributable to various risk factors. The analysis, conducted among 67,634 women in the French E3N cohort, shows that postmenopausal breast cancers are more often attributable to “behavioural” factors, such as an unhealthy diet, excess weight and alcohol consumption than “non-behavioural” factors. These data suggest...
Researchers at Inserm Unit 1194, “Montpellier Cancer Research Institute” (Inserm/University of Montpellier/Montpellier Regional Cancer Institute) have confirmed the value of a new test to identify cancer patients who will be free of sequelae following radiotherapy. This test, conducted on a blood sample taken from 500 breast cancer patients, treated in 10 centres in France, and monitored for 3 years, showed that women with a high rate of radiation-induced lymphocyte...
The vital role of the intestinal flora in successful immunotherapy has just been revealed in a study published in the journal Science. Intestinal bacteria have been identified that can improve the therapeutic response to this drug and reduce a side-effect, “inflammatory colitis,” regularly encountered with this treatment. This research implies that the efficacy of immunotherapy in oncology might in future be dictated by the composition of the patient’s intestinal flora....
Thanks to work done at Institute Curie by a team led by Fatima Mechta-Grigoriou, Inserm Research Director, it is now possible to identify, among women with aggressive ovarian cancer, those who could benefit from a promising targeted therapy.
Inserm teams led by Prof. Jean-Yves Blay and Christophe Caux in Lyon , and by Franck Tirode and Olivier Delattre in Paris have just demonstrated a new genetic variant in tumours that had not been identified until now
More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers at Inserm have just identified the role of a new virus, hitherto unsuspected, in the occurrence of a rare type of liver cancer.
Two teams of researchers from Inserm, CNRS, Centre Léon Bérard and Claude Bernard Lyon 1 University have discovered a molecule that may favour the production of these induced stem cells.
Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth.
A growing tumour exerts considerable ongoing abnormal pressure on the healthy neighbouring cells. The CNRS/UPMC/Institut Curie team directed by Emmanuel Farge, Inserm Research Director at Institut Curie, has just discovered that this force can induce tumour gene expression.
Une collaboration internationale conduite par le Professeur Thomas Baumert met en évidence qu’un anticorps monoclonal spécifiquement dirigé contre la claudine-1, permet de prévenir et de traiter une infection chronique par ce virus dans un modèle animal.