Two Inserm research teams have just shown that failure of the intestine to produce a lipid “messenger” is associated with Crohn’s disease, a common and highly disabling inflammatory bowel disease (IBD).
The vital role of the intestinal flora in successful immunotherapy has just been revealed in a study published in the journal Science. Intestinal bacteria have been identified that can improve the therapeutic response to this drug and reduce a side-effect, “inflammatory colitis,” regularly encountered with this treatment.This research implies that the efficacy of immunotherapy in oncology might in future be dictated by the composition of the patient’s intestinal flora....
L’Inserm s’engage dans le cadre de la COP21 : symposiums scientifiques, conférences pour le grand public.
Researchers from Inserm and physicians from the Department of Paediatric Endocrinology, Gynaecology and Diabetology at Necker Hospital for Sick Children (AP-HP, Inserm U1016, Paris Descartes University, Imagine Institute) have developed an improved treatment for a rare form of early childhood diabetes associated with cognitive disorders. Their work, conducted in collaboration with the Neurophysiology Department of Pitié-Salpêtrière Hospital, AP-HP, shows that a drug used for decades to treat type 2...
A Cerebrovascular Accident results from the interruption of blood flow to the brain. The deprivation of oxygen and essential nutrients causes brain cells to die, leading to permanent damage (speech or writing difficulty, memory problems, bodily paralysis to a greater or lesser extent), or even sudden death.
Each year, obesity kills 2.8 million people worldwide. When confronting morbid overweight—and its direct consequence, type 2 diabetes—surgery is used as a last resort. Strangely, in patients who have had such an operation, the diabetes disappears before and independently of weight loss. Inserm researchers, with the help of physicians from Bichat Hospital, AP-HP, have shown that the surgically reconfigured intestine might be at the root of this improved glycaemic...
Inserm is paying close attention to the level 2 incident, declared on 21 October 2015 by the French Nuclear Safety Authority (ASN), which occurred in a joint Inserm/University of Bordeaux laboratory.
In 2012, the Île-de-France Regional Health Agency initiated a regional project aimed at Reducing Infant and Perinatal Mortality (RéMI). This initiative was primarily focused on Seine-Saint-Denis, a district characterised by excess infant mortality (death before one year of age) and perinatal mortality (foetal deaths and deaths in the first week of life).
The team led by Didier Leys and Régis Bordet (UMR-S 1171, Lille 2 University, Inserm, Lille University Hospital) has identified a biomarker that makes it possible to predict the risk of haemorrhagic complications from thrombolytic treatment following a Cerebrovascular Accident (CVA or stroke).
Monday 12 October saw the start of the annual vaccination campaign, which will continue until the end of January 2016
Thanks to work done at Institute Curie by a team led by Fatima Mechta-Grigoriou, Inserm Research Director, it is now possible to identify, among women with aggressive ovarian cancer, those who could benefit from a promising targeted therapy.
