The team led by Claire Wyart, an Inserm researcher at the Brain and Spine Institute, has just demonstrated the ability of sensory neurons located in the spinal cord to modulate movement. In the zebrafish, the researchers have shown that activation of these neurons triggers locomotion when the animal is at rest, and inhibits it when the animal is moving. These results offer hope that it will one day be...
In one year’s time, French ESA astronaut Thomas Pesquet will take off for the International Space Station (ISS), on board which he will conduct scientific experiments prepared by researchers from Inserm. The scientific and technical programme for this ESA (European Space Agency) mission includes significant participation by France, managed by CNES (National Centre for Space Studies). Research projects from 3 Inserm laboratories will be conducted in orbit. Their purpose...
Researchers from Unit 825, “Brain imaging and neurological handicaps” show that the quality of communication between two structures in the brain predicts patient recovery at 3 months.
Initiated by the International Diabetes Federation and the World Health Organization, World Diabetes Day, which takes place next Saturday, 14 November, is aimed at sensitising and informing the general public about diabetes prevention and management. Diabetes, type 1 or type 2, is a chronic disease characterised by insufficient production of insulin, or by poor […]
Two Inserm research teams have just shown that failure of the intestine to produce a lipid “messenger” is associated with Crohn’s disease, a common and highly disabling inflammatory bowel disease (IBD).
The vital role of the intestinal flora in successful immunotherapy has just been revealed in a study published in the journal Science. Intestinal bacteria have been identified that can improve the therapeutic response to this drug and reduce a side-effect, “inflammatory colitis,” regularly encountered with this treatment. This research implies that the efficacy of immunotherapy in oncology might in future be dictated by the composition of the patient’s intestinal flora....
L’Inserm s’engage dans le cadre de la COP21 : symposiums scientifiques, conférences pour le grand public.
Researchers from Inserm and physicians from the Department of Paediatric Endocrinology, Gynaecology and Diabetology at Necker Hospital for Sick Children (AP-HP, Inserm U1016, Paris Descartes University, Imagine Institute) have developed an improved treatment for a rare form of early childhood diabetes associated with cognitive disorders. Their work, conducted in collaboration with the Neurophysiology Department of Pitié-Salpêtrière Hospital, AP-HP, shows that a drug used for decades to treat type 2...
A Cerebrovascular Accident results from the interruption of blood flow to the brain. The deprivation of oxygen and essential nutrients causes brain cells to die, leading to permanent damage (speech or writing difficulty, memory problems, bodily paralysis to a greater or lesser extent), or even sudden death.
Each year, obesity kills 2.8 million people worldwide. When confronting morbid overweight—and its direct consequence, type 2 diabetes—surgery is used as a last resort. Strangely, in patients who have had such an operation, the diabetes disappears before and independently of weight loss. Inserm researchers, with the help of physicians from Bichat Hospital, AP-HP, have shown that the surgically reconfigured intestine might be at the root of this improved glycaemic...