- 2017
- Press releases - 30.11.2017
Pancreatic Cancer: a “Multiomic” Study Identified Two Tumor Subtypes, and a Potential New Treatment Avenue
Juan Iovanna (Inserm Research Director) and his colleagues at the Marseille Cancer Research Center (Inserm/CNRS/Aix Marseille Université/Institut Paoli-Calmettes), in close collaboration with the “Tumor identity cards (CIT)” program run by the Ligue nationale contre le cancer and the University of Wisconsin (United States), have generated a “bank” of approximately 200 viable human pancreatic tumors, and cells derived from these tumors. The “multiomic” analysis of these tumors, i.e. the general characterization of all alterations in gene expression, epigenetic modifications of DNA methylation, has evidenced two main tumor subtypes. The specific characteristics of these subtypes, identified by the researchers, could open up new therapeutic approaches. The results of this research have been published in the journal Cell Reports.
- Press releases - 27.11.2017
An Edible Mushroom With Potential to Fight Human Genetic Diseases
Could a common mushroom help fight certain genetic diseases? Although surprising, this is indeed the new discovery made by French scientists from Inserm, the French National Museum of Natural History, the CNRS, Université de Lille, and the Institut Pasteur de Lille[1]. By examining numerous extracts, the scientists thus evidenced that the mushroom, Lepista inversa, acted significantly on three isolated cell lines taken from patients with cystic fibrosis. This research was published in .Plos One
- Press releases - 23.11.2017
Ribosome Plasticity: a New Avenue in Targeted Cancer Therapy
The “Nuclear Domains and Pathologies” team led by Jean-Jacques Diaz, Inserm Research Director at the Cancer Research Center of Lyon (Inserm/CNRS/Université Claude Bernard Lyon 1/Centre Léon Bérard), has recently demonstrated that one of the essential components of the “cellular machinery” that produces proteins – the ribosome – is altered in tumors. The researchers have observed that these modified ribosomes function differently in cancer cells, preferentially producing proteins that favor cancer cell proliferation and survival. This discovery opens up new possibilities for the development of innovative cancer therapies that target this abnormal machinery. This research has been published in Proceedings of the National Academy of Sciences (PNAS).
- Press releases - 22.11.2017
One Step Closer to Restoring Respiratory Function in Cystic Fibrosis?
A new study by Olivier Tabary and his colleagues at the Saint-Antoine Research Center (Inserm Unit 938/Université Pierre et Marie Curie (UPMC), Sorbonne Universities) has revealed a new mechanism that makes it possible to restore the functioning of a cell channel found particularly in the lung mucosa of cystic fibrosis patients. This transfer, usually operated by the CFTR protein, is deficient in patients with cystic fibrosis and known for forming the basis of the disease. The findings, published in Nature Communications, open up the possibility of a therapy that would enable sufferers to recover their respiratory function.
- Press releases - 20.11.2017
A crucial enzyme finally revealed
After 40 years of research, researchers at the CEA, the CNRS, the University of Grenoble-Alps, the University of Montpellier and the Inserm have finally identified the enzyme responsible for the tubulin cycle. Surprisingly, it is not one enzyme but two which control the cycle of this essential component of the cytoskeletal structure. This work opens up new prospects for the improved understanding of the role of tubulin, changes in the cycle of which are associated with cancers, cardiac diseases and neural disorders. These results were published on 16th November 2017 in the review Science.
- Press releases - 20.11.2017
December 1, 2017: World AIDS Day
Introduced by the World Health Organization in 1988 and observed in many countries each year since, this day aims to inform and raise awareness of the prevention, treatment and management of human immunodeficiency virus (HIV)/AIDS.
- What's on? - 20.11.2017
December 1, 2017: World AIDS Day
Friday December 1, 2017, is World AIDS Day. Introduced by the World Health Organization in 1988 and observed in many countries each year since, this day aims to inform and raise awareness of the prevention, treatment and management of human immunodeficiency virus (HIV)/AIDS. AIDS is a scourge that affects the world’s poorest countries and populations […]
- Press releases - 10.11.2017
The consumption of antioxidant-rich foods is associated with a lower risk of type 2 diabetes
A lower risk of type 2 diabetes has been observed among individuals consuming food rich in antioxidants. This effect is largely contributed by fruit, vegetables, tea and other hot beverages, as well as moderate consumption of alcohol, as shown in a recent study from an Inserm research group, published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD)
- Press releases - 08.11.2017
Efficacy of online nutritional coaching in patients with type 2 diabetes and abdominal obesity
A study coordinated by Dr. Boris Hansel and Prof. Ronan Roussel, from the Diabetes-Endocrinology and Nutrition Department at Hôpital Bichat – Claude-Bernard, AP-HP and the Cordeliers Research Center (Inserm/Pierre and Marie Curie University, Paris Diderot, Paris Descartes University) shows that online nutritional coaching -an automated nutritional support program- improves dietary habits and glycemic control in patients with type 2 diabetes and abdominal obesity.
- Press releases - 06.11.2017
World Diabetes Day
Celebrated every November 14 since its creation in 1991, World Diabetes Day is an opportunity to raise collective awareness of the condition and, above all, the resources deployed to manage it. Diabetes refers to consistently higher than normal blood sugar levels (hyperglycemia).