Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy
Estelle Woldt1,2,3,4,5 *, Yasmine Sebti1,2,3,4,5 *, Laura A. Solt6, Christian Duhem1,2,3,4,5, Steve Lancel4,7, Jérôme Eeckhoute1,2,3,4,5, Matthijs K.C. Hesselink8, Charlotte Paquet1,2,3,4,5, Stéphane Delhaye1,2,3,4,5, Youseung Shin6, Theodore M. Kamenecka6, Gert Schaart8, Philippe Lefebvre1,2,3,4,5, Rémi Nevière4,7, Thomas P. Burris6, Patrick Schrauwen8, Bart Staels1,2,3,4,5, Hélène Duez1,2,3,4,5Affiliations: 1. Institut Pasteur de Lille, Lille F-59019, France 2. INSERM UMR 1011 'Nuclear Receptors, Cardiovascular Diseases and Diabetes’, Lille F- 59019, France 3. Université Lille Nord de France, Faculté des Sciences Pharmaceutiques et Biologiques et Faculté de Médecine, Lille F-59006, France 4. UDSL, F-59000, Lille, France 5. European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France 6. Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA. 7. Département de Physiologie (EA 4484), Faculté de Médecine, Université Lille Nord de France, place de Verdun, Lille cedex 59045, France. 8. School for Nutrition, Toxicology and Metabolism, depts of Human Biology and Human Movement Sciences, Maastricht University Medical Center, NL-6200 MD Maastricht, The Netherlands. * have equally contributed Nature Medicine, 14 juillet 2013 https://dx.doi.org/10.1038/nm.3213