Press releases

Identification d’un nouveau gène suppresseur de tumeur

Press release | 29 Jun 2011 - 17h05 | By INSERM PRESS OFFICE
Cancer
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Press release – Inserm press room Identification d’un nouveau gène suppresseur de tumeur Link : https://presse.inserm.fr/en/francais-identification-dun-nouveau-gene-suppresseur-de-tumeur/13792/

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A new pathway for modulating anti-tumoral immune response

Researchers from Inserm, CNRS, Paris-Sud University, Gustave Roussy, and Institut Curie have identified a new agent in regulating PD-L1 gene expression: the eIF4F complex, which plays a role in controlling protein synthesis. ...
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Metastatic Lung Cancer: A Targeted Therapy to Improve Treatment Efficacy

When faced with the most aggressive forms of lung cancer, how can the efficacy of chemotherapy be increased? Teams from Inserm, Université Paris Descartes and the Paris public hospitals system AP-HP have maybe hit on a solution. They have developed a targeted ...
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Researcher Contact

Olivier Bernard Unité Inserm 985 "Génétique des tumeurs" Tél. : 01 42 11 42 33

Sources

"TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis" Cyril Quivoron,1,2,3,14 Lucile Couronné,1,2,3,14 Véronique Della Valle,1,2,3,14 Cécile K Lopez,1,2,3 Isabelle Plo,2,3,4 Orianne Wagner-Ballon,4,5 Marcio Do Cruzeiro,6 Francois Delhommeau,4,7 Bertrand Arnulf,8 Marc-Henri Stern,9 Lucy Godley,10 Paule Opolon,3 Hervé Tilly,11 Eric Solary,2,3,4 Yannis Duffourd,3 Philippe Dessen,1,2,3 Hélène Merle-Beral,12 Florence Nguyen-Khac,12 Michaëla Fontenay,13 William Vainchenker,2,3,4 Christian Bastard,11,15 Thomas Mercher,1,2,3,15 Olivier A Bernard1,2,3,15,* (1) Inserm, U985, 94805, Villejuif, France (2) Université Paris-Sud, 91400, Orsay, France (3) Institut Gustave Roussy, 94805, Villejuif, France (4) Inserm, U1009, 94805, Villejuif, France (5) Hôpital Henri Mondor, 94000, Créteil, France (6) Plateforme de Recombinaison Homologue, Institut Cochin, Inserm U1016; Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche (UMR) 8104; Université Paris Descartes, Faculté de Médecine Paris Descartes, 75014, Paris, France (7) Université Pierre et Marie Curie ; Hôpital Saint Antoine, Paris, France (8) EA 3963, Université Paris VII, Hôpital Saint-Louis, 75010, Paris, France (9) Inserm, U830, Institut Curie, 75005, Paris, France (10) Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. (11) Inserm, U918, Université de Rouen, Centre Henri Becquerel, 76038, Rouen, France (12) Service d’Hématologie Biologique, Hôpital Pitié-Salpêtrière, APHP; Université Pierre et Marie Curie-Paris 6; Inserm U872, 75005, Paris, France Cancer Cell 30 juin 2011

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