Une famille avec de nombreux cancers inexpliqués révèle que certaines prédispositions aux cancers du rein sont liées à des mutations du gène BAP1. Porté sur le chromosome 3, ce gène était déjà connu pour prédisposer à des cancers oculaires (mélanome uvéal) et de la plèvre (mésothéliome). Ces travaux réalisés par Marc-Henri Stern du laboratoire Génétique et Biologie des Cancers (Institut Curie/Inserm U830) en coordination avec le Pr Dominique Stoppa-Lyonnet...
Thanks to work carried out by the Massachusetts Institute of Technology in Boston, Eric Burguière, an Inserm researcher working in the MHI research centre and his co-workers have succeeded in reducing the compulsive behaviour of mice using optogenetics, a technique that combines light stimulation with genetic engineering.
The physicians are not given enough information about the adverse effects of drugs during presentations made by medical sales representatives from pharmaceutical companies. And yet, these same physicians are willing to prescribe at least some of the presented drugs. Dr. Geneviève Durrieu (from the Pharmaco-epidemiology team assessing the use of medication and the risks involved, Unit 1027 "Epidemiology and public health analyses: risks, chronic diseases and handicaps" - Inserm...
The burden of mortality and morbidity in the perinatal period – pregnancy, childbirth, and the postpartum – remains a major concern in Europe. Over 5 million women deliver babies in European countries every year.
An exploratory study published today by Sylvaine Cordier and her team and researchers from Inra in Toulouse, suggests that environmental exposure to complex pesticide mixtures could led to metabolic disturbance in pregnant women.
Over the whole school year, 20 middle school and high school pupils were seen each month in 5 neuroscience laboratories specializing in the study of addictions.
Claire Hivroz, INSERM Research Director and her colleagues recently showed in an article published in Nature immunology how a specific protein known as VAMP7 is essential for transporting the signal produced by the ligand–TCR link.
Although excessive quantities of cholesterol in the body are known to have adverse effects on health, researchers might polish up its reputation via one of its derivatives.
Scientists from the Institut Pasteur, Inserm and CNRS, have identified a human-specific factor involved in the replication of Chikungunya virus which accounts for the species specificity of this virus.
A l’occasion du comité de suivi annuel du schéma national pour les handicaps rares qui s’est tenu le 30 avril 2013, et a été présidé par Mme Marie-Arlette Carlotti, Ministre chargée des personnes handicapées et de la lutte contre l'exclusion, l’Inserm rend publique l’expertise collective « Handicaps rares, contextes, enjeux et perspectives. »
Le suivi biologique des patients infectés par le VIH et sous traitement antirétroviral s’effectue dans les pays du Nord par des mesures régulières de la charge virale du VIH et des lymphocytes CD4 : il est peu pratiqué dans les pays du Sud en raison de son coût élevé et du manque d’équipement des laboratoires (surtout en milieu rural).
