They observed that these individuals were deficient in intestinal bacteria (in both quantity and diversity) and were at greater risk of developing cardio-metabolic diseases.
A research team from Toulouse has just elucidated the mechanisms behind the differences in iron absorption between men and women. The team used mice to demonstrate how the action of testosterone can be “countered” with a drug already used in the treatment of some bronchial cancers.
Une nouvelle cible pharmacologique permettant d'améliorer le fonctionnement du muscle vient d'être découverte chez la souris par l'équipe d'Hélène Duez, chargée de recherche à l'Inserm dans l'unité 1011 "Récepteurs nucléaires, maladies cardiovasculaires et diabète" (Inserm/Université Lille 2 droit et santé/Institut Pasteur de Lille) dirigée par Bart Staels.
Patrick Collombat, Inserm Research Director and head of the Avenir team at the Institut de Biologie Valrose in Nice, has published new results concerning Type I diabetes. Researchers show that, in mice, the pancreas contains cells capable of being converted into insulin-producing β cells, something that can be done at any age.
The Inserm researchers at unit 1018, "The Epidemiology and Public Health Research Centre", working in collaboration with researchers from England and Finland have demonstrated that it is essential to be vigilant about this and to take it very seriously when people say that they are stressed, particularly if they believe that stress is affecting their health.
Certain food contaminants are suspected of triggering metabolic disorders, or of worsening them, particularly when they accompany a high-fat diet. In order to get a better understanding of these effects, researchers from the Inserm cardiovascular, metabolism, diabetology and nutrition unit introduced a "cocktail" of contaminants mixed with low doses of dioxin, PCB, bisphenol A and phtalates into the feeding of mice that had already been rendered obese by...
Are teeth the latest victims of bisphenol A? Yes, according to the conclusions of work carried out by the research team led by Ariane Berdal of the Université Paris-Diderot and Sylvie Babajko. The researchers have shown that the teeth of rats treated with low daily doses of BPA could be damaged by this. Analysis of the damage shows numerous characteristics that are common with a recently identified pathology of...
C’est un équipage inhabituel qui s’apprête à décoller du cosmodrome de Baïkonour le vendredi 19 avril 2013. Dans le cadre d’une expérience de biologie médicale, 15 souris astronautes vont passer un mois en orbite autour de la Terre à bord d’un biosatellite automatique BION. L’objectif de cette mission est d’étudier les conséquences fonctionnelles d’un voyage spatial, d’une part sur le système cardio-vasculaire et, d’autre part, sur les systèmes musculaires...
In this prospective study, led by Dr Richard Moreau, INSERM Research Director, researchers studied a cohort of 1343 patients from 12 European countries. The results, published in the learned journal Gastroenterology, describe, for the first time, the specific profile of sufferers from this syndrome that is associated with cirrhosis.
Research performed by the Neurology Department and Stroke Reception and Treatment Unit at the Bichat Hospital (AP-HP/ Paris University Diderot) and the associated INSERM Unit 698 (Prof. Amarenco, Dr Olivier Meilhac) has highlighted the benefits of good cholesterol in reducing bleeding complications in the only treatment available for embolic stroke. The results of this experiment, performed on the rat, have just been published in Stroke .
Liver and skeletal muscle resistance to the action of insulin is an early sign of the development of Type 2 Diabetes. The INSERM team at the "Obesity Research Laboratory " in the Institut des Maladies Métaboliques and Cardiovasculaires (INSERM / Université Toulouse III - Paul Sabatier), headed by Dominique Langin, has shown through results published this week, that there is an association between lipolysis (mobilisation of fat in response...
