For the first time, the team led by Gérard Gradwohl, an Inserm Research Director at the Institute of Genetics and Molecular and Cellular Biology, Illkirch (IGBMC/Inserm-CNRS-University of Strasbourg), has shown that the Rfx6 gene is essential for the functioning of the cells that produce insulin, the pancreatic beta cells.
A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation – Biotherapies 504 [CIC-BT 504]), and their collaborators at Institut Curie and AP-HP (George Pompidou European Hospital) has succeeded in finding a combination of drugs that reduces the risk of rejection following a skin graft. When tested in mice, this treatment seems effective, since no sign...
Eating disorders (ED) such as anorexia nervosa, bulimia, and binge eating disorder affect approximately 5-10% of the general population, but the biological mechanisms involved are unknown. Researchers at Inserm Unit 1073, “Nutrition, inflammation and dysfunction of the gut-brain axis” (Inserm/University of Rouen) have demonstrated the involvement of a protein produced by some intestinal bacteria that may be the source of these disorders.
Researchers at Inserm, led by Claude Gronfier (Inserm Unit 846: Stem Cell and Brain Institute), have, for the first time, conducted a study under real conditions on the body clocks of members of the international polar research station Concordia. The researchers have shown that a particular kind of artificial light is capable of ensuring that their biological rhythms are correctly synchronised despite the absence of sunlight.
By combining fundamental research and monitoring a single cohort of kidney-transplant patients with antiphospholipid syndrome, the researchers have highlighted a beneficial effect of sirolimus, commonly used as an immunosuppressor in organ transplants, to prevent recurrence of vascular lesions on the transplanted kidney.
Adrenocortical carcinoma (also known as adrenal cortex cancer or ACC), is a generally aggressive tumour, with a mean survival rate of less than five years for those affected. Apart from metastasis, it exposes the patients to manifestations such as high blood pressure, diabetes, decreased potassium level, infections, etc. There is, however, some patient-dependent variation in tumour development. The team led by Prof. Bertherat at the Cochin Institute (Inserm –...
Scientists from INRA and INSERM (France) have shown that Elafin, a human protein, plays a key role against the inflammatory reaction typical of celiac disease (gluten intolerance).
European cutting-edge research will be attended at the annual meeting of the American Association for the Advancement of Science (AAAS) in Chicago.
French-Swedish team including researchers from CNRS, Inserm and the Université Claude Bernard Lyon 1 (Unité Inserm 855 “Nutrition et Cerveau”) has succeeded in elucidating this mechanism, which involves the intestinal flora and the ability of the intestine to produce glucose between meals.
Professor André Syrota, Inserm Chief Executive, and Professor Peretz Lavie, President of Technion, will sign the agreement to create a new Associated International Laboratory (AIL) on 17 December 2013. This artificial 'electronic nose' project brings together Inserm Unit 999 'Pulmonary Hypertension' and the Russell Berrie Nanotechnology Institute Chemical Engineering department, directed by Professor Hossam Haick.