Platelets play a role in severe lung infections associated with flu viruses. This has been highlighted for the first time by a team of researchers from France's National Institute for Agricultural Research (Inra), National Institute for Health and Medical Research (Inserm) and Claude Bernard (Lyon 1) University
Une collaboration internationale conduite par le Professeur Thomas Baumert met en évidence qu’un anticorps monoclonal spécifiquement dirigé contre la claudine-1, permet de prévenir et de traiter une infection chronique par ce virus dans un modèle animal.
For 5 weeks, 5 international research teams will conduct a scientific expedition in Nepal, in the heart of the Himalayas, close to the summit of Mount Manaslu (8,156 m). The French component of the expedition, coordinated by a researcher from Inserm (Inserm/Université Joseph Fourier), will conduct an original project on the impact of altitude on the brain and heart, and on sleep disturbances induced by altitude. The French researchers...
A team of Inserm researchers from the Cardio-Thoracic Research Centre of Bordeaux has demonstrated the clinical efficacy of gallopamil in 31 patients with severe asthma.
University of Nantes, Inserm and Thinkovery have joined forces to produce a new kind of MOOC (Massive Open Online Course).
On the 21 October 2014, Professor Philippe Menasché and his team from the cardiovascular surgery service of the Georges Pompidou European Hospital, AP-HP, carried out a transplant of cardiac cells derived from human embryonic stem cells
For the first time, the team led by Gérard Gradwohl, an Inserm Research Director at the Institute of Genetics and Molecular and Cellular Biology, Illkirch (IGBMC/Inserm-CNRS-University of Strasbourg), has shown that the Rfx6 gene is essential for the functioning of the cells that produce insulin, the pancreatic beta cells.
A research team bringing together José Cohen and Philippe Grimbert (Inserm Unit 955/Université Paris Est Créteil [UPEC] and the Centre for Clinical Investigation – Biotherapies 504 [CIC-BT 504]), and their collaborators at Institut Curie and AP-HP (George Pompidou European Hospital) has succeeded in finding a combination of drugs that reduces the risk of rejection following a skin graft. When tested in mice, this treatment seems effective, since no sign...
Eating disorders (ED) such as anorexia nervosa, bulimia, and binge eating disorder affect approximately 5-10% of the general population, but the biological mechanisms involved are unknown. Researchers at Inserm Unit 1073, “Nutrition, inflammation and dysfunction of the gut-brain axis” (Inserm/University of Rouen) have demonstrated the involvement of a protein produced by some intestinal bacteria that may be the source of these disorders.
Researchers at Inserm, led by Claude Gronfier (Inserm Unit 846: Stem Cell and Brain Institute), have, for the first time, conducted a study under real conditions on the body clocks of members of the international polar research station Concordia. The researchers have shown that a particular kind of artificial light is capable of ensuring that their biological rhythms are correctly synchronised despite the absence of sunlight.
By combining fundamental research and monitoring a single cohort of kidney-transplant patients with antiphospholipid syndrome, the researchers have highlighted a beneficial effect of sirolimus, commonly used as an immunosuppressor in organ transplants, to prevent recurrence of vascular lesions on the transplanted kidney.