Des chercheurs ont identifié un nouveau mécanisme cellulaire qui altère la formation du placenta et pourrait ainsi provoquer des complications graves pendant la grossesse. Il est lié à la production d’interféron, une molécule qui est produite en réponse à certaines infections, notamment virales.
Anaphylactic shock, an exacerbated allergic reaction that can prove fatal, is sometimes caused by the use of drugs during surgery. In most of these extreme reactions, evidence can be provided that patients have anti-drug antibodies of the IgE class. In 10 to 20% of anaphylactic cases evidence for the involvement of anti-drug IgE is lacking. Anti-drug IgE enable activation of mast cells and basophils that release histamine, a potent...
Researchers from Inserm and Université de Rennes recently identified a new bacterial toxin which they transformed into potent antibiotics active against various bacteria responsible for human infections.
A joint team of researchers from Inserm and the University of Paris has investigated the frequency of physical abuse during pregnancy, its consequences for the mother and child, and the characteristics associated with this violence.
Inserm is reaching out to a new audience among the general public this summer by taking part in two events that bring together art and science in a mutually enriching way: the 8th Recherche de l'art (Art of Research) exhibition at the Rencontres d'Arles, in partnership with the École nationale supérieure de la photographie, and the 10th edition of the binôme program at the Avignon Festival, led by the...
An Inserm team has provided the first description of the behavior and language of the neurons responsible for memory consolidation during sleep.
Researchers have shown that using immunotherapies at very early stages could potentially help prevent cancer.
Les ataxies spinocérébelleuses sont des maladies génétiques neurodégénératives du cervelet et du tronc cérébral qui entrainent de nombreux troubles moteurs, et dont la forme la plus connue est la maladie de Machado-Joseph. Une équipe de l’Institut du cerveau et de la moelle épinière, a découvert avec son équipe le rôle crucial d’une enzyme qui permet d’améliorer les symptômes de la maladie chez la souris.
Despite the increasing research into and recognition of the role of particulate matter in the excess mortality caused by air pollution, it is still poorly understood. A research team used an innovative method based on the biomonitoring of metal levels in mosses in rural France. Their findings point to a link between long-term exposure to atmospheric metals and excess mortality, even in areas remote from major sources of emissions.
Inserm researcher Jérôme Galon has been honored by the European Patent Office (EPO) for his Immunoscore®, a test that predicts relapse risk in patients with certain forms of cancer. An achievement that encapsulates the missions and results of Inserm, a research institute serving good health for all.