Des chercheurs Inserm de l’équipe d’épidémiologie des maladies allergiques et respiratoires (EPAR) ont analysé les données sur les risques de naissances d’enfants accusant un retard de croissance liés à la pollution atmosphérique. Cette étude révèle que l’impact de la pollution atmosphérique durant la grossesse ainsi que les répercussions sur l’enfant après la naissance coûtent cher. Le montant pour la société est ainsi estimé à 1.2 milliard d’euros. Ces résultats...
A multidisciplinary team of researchers from CNRS, INSERM and Université Toulouse III – Paul Sabatier has developed a hydrogel that can grow, develop and differentiate neural stem cells. This biomaterial could provide new paths for the development of in vitro cellular models of brain tissue or of in vivo tissue reconstruction. This work is published in ACS Applied Materials & Interfaces on May 14, 2018.
In a paper published in the journal Science Translational Medicine , Guy and his team Gorochov research center CIMI (Inserm / Université Sorbonne) and Immunology Department at the Pitié-Salpêtrière Hospital, AP-HP, reveal that our IgA act as conductor of the intestinal microbiota. They effectively prevent intestinal colonization by the oral flora and promote the presence of certain bacteria, totally innocent of infectious standpoint, but playing a beneficial role.
A Franco-American team involving researchers from Inserm, Université Paris-Descartes and doctors grouped in the Institute Imagine the hospital Necker-Enfants Malades AP-HP and Rockefeller University New York discovered a genetic cause of Whipple's disease, chronic intestinal pathology. By studying families with 4 members developed symptoms, the team found that the mutation of the gene causes IRF4 an impaired immune response to the bacteria Tropheryma whippleiAt the origin of the disease....
A trial sponsored by AP-HP and conducted by teams of Beaujon Hospital, AP-HP, Inserm and Université Paris Diderot was set up to establish an indicator that reflects the severity of liver disease in patients with cirrhosis. Coordinated by Professor Pierre-Emmanuel Rautou and Dr. Audrey Payancé the Hepatology Service of Beaujon Hospital, AP-HP, this study establishes that measurement microvesicles rate from liver and circulating in the blood greatly improves prediction...
Tuesday May 1 is World Asthma Day - a day to educate and raise public awareness to improve the diagnosis and treatment of asthma.
With the genome editing CRISPR-case.9 technique, researchers at INSERM, the hospital Necker Children-AP-HP, and Université Paris Descartes in the Institute Imagine managed to reactivate a gene that may improve the appearance of red blood cells of patients with hemoglobinopathies such as sickle cell anemia and beta-thalassemia. The teams Annarita Miccio, Inserm researcher, Prof. Marina Cavazzana AP-HP and Isabelle André-Schmutz, Inserm researcher show this new avenue of research and treatment...
In an article in the New England Journal of Medicine published on April 19, the intermediate results of a clinical trial (HGB-205) led by Pr. Marina Cavazzana and her teams at the Necker-Enfants malades hospital AP-HP in collaboration with the Imagine Institute (AP-HP/Inserm/Paris Descartes University) as well as those of an international multicenter trial (HGB-204) conducted in the United States, Thailand and Australia, show that gene therapy is effective...
How can we preserve renal function in people with a chronic kidney disease? Can dialysis be avoided or delayed? To answer these questions and many others, Inserm and Université Paris-Sud have set up the CKD-REIN1 cohort study, led by Bénédicte Stengel. Today it has produced its first results. According to the study, conducted with more than 3,000 patients, several priorities may improve the management of kidney disease. These priorities...
The thirteenth annual World Immunization Week will take place from April 23 to 29, 2018. The campaign, created by the World Health Organization (WHO), undertakes to raise awareness about the stakes of vaccine protection.