The team of Professor Amarenco, head of the neurology department at the Hospital Bichat Claude Bernard, AP-HP, professor at the University Paris Diderot – Inserm studied the risk of recurrence of stroke for patients who received a care in the 24 hours following the occurrence of a transient ischemic attack. The researchers demonstrate that 1 to […]
A trial sponsored by AP-HP and conducted by teams of Beaujon Hospital, AP-HP, Inserm and Université Paris Diderot was set up to establish an indicator that reflects the severity of liver disease in patients with cirrhosis. Coordinated by Professor Pierre-Emmanuel Rautou and Dr. Audrey Payancé the Hepatology Service of Beaujon Hospital, AP-HP, this study establishes that measurement microvesicles rate from liver and circulating in the blood greatly improves prediction...
What if immune system efficacy against cancerous cells could be reinforced by a diet in which calories are not reduced but nutrients are precisely determined? This what Inserm researchers from Université Côte d’Azur, through a study of the effects of restrictive diets on tumor growth in mice, have been exploring. They have observed that a low-protein diet restricts tumor development by increasing immune response. The findings, to be published...
The rapidly-developing medical imaging field could well have found a novel technique in which multiple facets of a living being can be observed in real time and non-invasively. Teams from the Langevin Institute (ESPCI Paris - PSL University / CNRS), the biomedical ultrasound Technology Research Accelerator (Inserm A.R.T.) and the Paris-Cardiovascular Research Center (Inserm / Paris Descartes University) have developed a new medical imaging instrument which combines positron emission...
What if the symptoms and seriousness of certain inflammatory diseases were linked to time of day? Researchers from Inserm, Institut Pasteur de Lille and Université de Lille[1] have been working on this hypothesis, after noting that the seriousness and mortality associated with fulminant hepatitis were dependent on the time at which the disease was induced. Their study, conducted on human cells and mice, shows that the anti-inflammatory action of...
A recent study conducted by Inserm researchers within Irset[1] has shown that sustained ibuprofen use in young male athletes induces a hormonal imbalance known as "compensated hypogonadism", usually observed in elderly males. This situation arises due to the negative effects of ibuprofen on testosterone production, and on the production of two other testicular hormones. These results have been published in Proceedings of the National Academy of Sciences.
Vincent Sauzeau, Inserm researcher and his team located at the Nantes Thorax Institute[1] (Inserm, CNRS, University of Nantes, Nantes University Hospital) have recently discovered the major role played by the Rac1 protein in the development of bronchial hyperresponsiveness associated with allergic asthma. Researchers will use this new therapeutic target to reduce bronchoconstriction and pulmonary inflammation in patients. This article has been published in The Journal of Allergy and Clinical...
A new study by Olivier Tabary and his colleagues at the Saint-Antoine Research Center (Inserm Unit 938/Université Pierre et Marie Curie (UPMC), Sorbonne Universities) has revealed a new mechanism that makes it possible to restore the functioning of a cell channel found particularly in the lung mucosa of cystic fibrosis patients. This transfer, usually operated by the CFTR protein, is deficient in patients with cystic fibrosis and known for...
A study coordinated by Dr. Boris Hansel and Prof. Ronan Roussel, from the Diabetes-Endocrinology and Nutrition Department at Hôpital Bichat – Claude-Bernard, AP-HP and the Cordeliers Research Center (Inserm/Pierre and Marie Curie University, Paris Diderot, Paris Descartes University) shows that online nutritional coaching -an automated nutritional support program- improves dietary habits and glycemic control in patients with type 2 diabetes and abdominal obesity.
The intestinal microbiota still has surprises in store. The mode of action of a probiotic bacteria used in the symptomatic treatment of pain in irritable bowel syndrome has been revealed in a new study conducted by scientists from Inserm, Université de Toulouse and CHU de Toulouse [1] within the Digestive Health Research Institute (Inserm/INRA/Université Toulouse III – Paul Sabatier, ENVT). The bacteria produces a neurotransmitter (GABA) which, when bound to...