France will be hosting the UEFA EURO 2016 Football Championships from Friday 10 June to Sunday 10 July. During this competition, many parts of the players’ bodies will be severely tested.Although the benefits of regular physical activity on physical and mental health have been demonstrated by many studies, what are the risks associated with excessive physical exercise? What methods would allow athletes to optimise their physical abilities? Do some...
A study from Inserm, Paris Descartes University and Sainte Anne Hospital suggests that anorexia nervosa might not be explained by fear of gaining weight, but by the pleasure of losing it... and that the phenomenon might be genetically influenced. Published in Translational Psychiatry, this study, directed by Prof. Gorwood, head of the Clinic for Mental and Brain Diseases, challenges the notion of fear of weight gain in anorexia patients.
Des chercheurs de l'Inserm et de l'Université Pierre et Marie Curie du Centre de Recherche des Cordeliers, en collaboration avec des chercheurs de l'institut Karolinska en Suède, ont décrit le mécanisme par lequel le facteur GPS2 réprime la survenue du diabète de type 2 chez les personnes obèses. Ces travaux, publiés dans la revue Nature Medicine, mettent en lumière l'importance de l'épigénome dans l'apparition de la maladie.
Initiated by the United Nations, World Environment Day is celebrated on 5 June every year in order to encourage awareness of the world environment, and stimulate individual actions.At Inserm, there is active ongoing research to identify the impacts of our environment on health, especially the effects of atmospheric pollution, endocrine disruptors and their consequences for reproductive function, and the relationship between environment and cancers.[1]
Finding new, more effective and personalised treatments for cancer is the challenge of many researchers. A challenge that has been successfully met by a team from Inserm led by Stéphane Rocchi (Inserm Unit 1065, “Mediterranean Center for Molecular Medicine”), which has just synthesised and developed new drugs for melanoma. One of them, known as HA15, reduces the viability of melanoma cells without being toxic for normal cells. This work...
Doctors should rethink how they treat patients who have suffered the deadliest form of stroke, a clinical trial suggests.The study recommends a change in guidelines for treating any patients who have had a stroke caused by bleeding into the brain – known as intracerebral haemorrhage (ICH) – while regularly taking aspirin.
A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response. Scientists from the Institut Pasteur and Inserm observed that CD4+ T immune cells in these patients, recruited from the ANRS CO21 CODEX cohort, were...
For the first time, scientists in the Center for Interdisciplinary Research in Biology (CNRS/INSERM/Collège de France) have produced direct evidence that the long-term storage of memories involves a dialogue between two brain structures, the hippocampus and cortex, during sleep; by enhancing this dialogue, they succeeded in triggering the consolidation of memories that would otherwise have been forgotten. This work is published in Nature Neuroscience on 16 May 2016.
Setting one’s alarm an hour or two earlier to run, meditate, read or even cook is a trend that is attracting many followers in France, also known as “morningophiles.” Recommended by Hal Elrod in his book The Miracle Morning, this lifestyle, which started in the United States, extols the virtues of waking up very early in the morning, as a source of well-being and productivity.
In 2015, a study conducted by Pierre Meneton, entitled “Unemployment is associated with high cardiovascular event rate and increased all-cause mortality in middle-aged socially privileged individuals,” was published in the International Archives of Occupational and Environmental Health.
