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Researchers develop an ultrasound probe capable of imaging an entire organ in 4D

For the first time, a team of Inserm researchers from the Physics for Medicine Institute Paris (Inserm/ESPCI Paris-PSL/CNRS) has succeeded in mapping the blood flow of an entire organ in animals (heart, kidney and liver) with great precision, in four dimensions: 3D + time. This new imaging technique, when applied to humans, could both improve our understanding of the circulatory system (veins, arteries, vessels and lymphatic system) and facilitate the diagnosis of certain blood circulation-related diseases.

28 Oct 2025 | Health technologies

Subretinal implant partially restores vision in AMD patients

Age-related macular degeneration (AMD) causes progressive vision loss in many elderly people, and no treatment is available for the so-called atrophic form of the disease. A neurostimulation system called Prima, including a subretinal implant, could change all that.

20 Oct 2025 | Neurosciences, cognitives sciences, neurology and psychiatry

Level of processing of plant products: impact on cardiovascular health

Consumption of plant-based products is associated with better cardiovascular health, provided they are of good nutritional quality and not or minimally processed. This is the finding of a research team from INRAE, Inserm, Sorbonne Paris Nord University and Cnam, based on analysis of health data from a cohort of 63,835 adults.

07 Oct 2025 | Public health

Astrocytes, the unexpected conductors of brain networks

A collaborative French-Swiss study reveals a previously unknown role for astrocytes in the brain's information processing.

24 Sep 2025 | Neurosciences, cognitives sciences, neurology and psychiatry

Consumption of food additives during pregnancy: effects on offspring microbiota increase susceptibility to inflammatory diseases

A study conducted in mice by scientists from the Institut Pasteur and Inserm reveals that maternal consumption of dietary emulsifiers can have a negative impact on the gut microbiota of their offspring.

19 Sep 2025 | Immunology, inflammation, infectiology and microbiology

Massaging the skin to vaccinate: a possible alternative to injections?

What if vaccination could be administered by simple skin application rather than injection? A team of researchers from Inserm, Institut Curie, and King's College London investigated the impact of external mechanical constraints (skin stretching, friction, etc.) on skin impermeability in animals and humans.

17 Sep 2025 | Cancer Immunology, inflammation, infectiology and microbiology

Economic inequalities could contribute to France’s recent rise in neonatal mortality

With neonatal mortality on the increase in France, a new study by Inserm, Paris Cité University, Inrae, Paris Nord University and APHP shows that it could be linked to socioeconomic inequalities. Using their social deprivation index adjusted for the perinatal period, the researchers observed that the risk of neonatal death is higher for mothers living in deprived municipalities.

16 Sep 2025 | Public health

A new antibody-drug conjugate shows promising results in metastatic breast cancer

A new study, published in Nature Medicine, highlights the efficacy of patritumab deruxtecan (HER3-DXd), an antibody HER3-directed-drug conjugate (ADC), in patients with hormone receptor-positive metastatic breast cancer who had already received multiple treatments, including hormone therapy, chemotherapy, and targeted therapies.

05 Sep 2025 | Cancer

A human protein inherited from bacteria reveals an overlooked aspect of human immunity

In recent years, scientists have been exploring unexpected links between human proteins involved in the body’s defense mechanisms and certain bacterial immune proteins. Focusing on conserved immune domains originating from bacteria, termed “ancestral immune”, a team of researchers from Institut Curie, Institut Pasteur, and Inserm identified a novel human immune protein, SIRal.

24 Jul 2025 | Immunology, inflammation, infectiology and microbiology

A new class of molecules against cancer cells refractory to standard treatments

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed by scientists at Institut Curie, the CNRS, and Inserm.

07 May 2025 | Cancer

Hyperglycémie : vers une meilleure compréhension de son impact délétère sur la peau

Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as "post-treatment controllers," are able to maintain an undetectable viral load even after stopping treatment. Scientists from the Institut Pasteur, Inserm and the Paris Public Hospital Network (AP-HP) identified specific immunogenetic characteristics in a group...

30 Apr 2025 | Circulation, metabolism, nutrition Genetics, genomics and bioinformatics

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