While Bacillus cereus is well known as a source of food infections, researchers from INRA and ANSES, working with doctors at nine French hospitals[1] including those in the Paris Public Hospital System (AP-HP), have demonstrated for the first time that this bacterium is also responsible for inter- and intra-hospital nosocomial contamination. This study, conducted in 39 patients between 2008 and 2012, also found strains of B. cereus in the hospital environment capable of causing...
Des chercheurs Inserm de l’équipe d’épidémiologie des maladies allergiques et respiratoires (EPAR) ont analysé les données sur les risques de naissances d’enfants accusant un retard de croissance liés à la pollution atmosphérique. Cette étude révèle que l’impact de la pollution atmosphérique durant la grossesse ainsi que les répercussions sur l’enfant après la naissance coûtent cher. Le montant pour la société est ainsi estimé à 1.2 milliard d’euros. Ces résultats...
A trial sponsored by AP-HP and conducted by teams of Beaujon Hospital, AP-HP, Inserm and Université Paris Diderot was set up to establish an indicator that reflects the severity of liver disease in patients with cirrhosis. Coordinated by Professor Pierre-Emmanuel Rautou and Dr. Audrey Payancé the Hepatology Service of Beaujon Hospital, AP-HP, this study establishes that measurement microvesicles rate from liver and circulating in the blood greatly improves prediction...
In an article in the New England Journal of Medicine published on April 19, the intermediate results of a clinical trial (HGB-205) led by Pr. Marina Cavazzana and her teams at the Necker-Enfants malades hospital AP-HP in collaboration with the Imagine Institute (AP-HP/Inserm/Paris Descartes University) as well as those of an international multicenter trial (HGB-204) conducted in the United States, Thailand and Australia, show that gene therapy is effective...
How can we preserve renal function in people with a chronic kidney disease? Can dialysis be avoided or delayed? To answer these questions and many others, Inserm and Université Paris-Sud have set up the CKD-REIN1 cohort study, led by Bénédicte Stengel. Today it has produced its first results. According to the study, conducted with more than 3,000 patients, several priorities may improve the management of kidney disease. These priorities...
One of the major challenges identified by the WHO in efforts to eradicate the hepatitis C virus (HCV) is the diagnosis of chronic cases that are generally asymptomatic. Major progress is required for new diagnostic techniques that can be "decentralized", in other words accessed by populations and countries with limited resources. Scientists from the Institut Pasteur and Inserm, in collaboration with the company genedrive, have developed and validated a...
A veritable sensor: a team of Inserm and CNRS researchers at the Institute of Pharmacology and Structural Biology (IPBS, CNRS/Paul Sabatier University – Toulouse III) has identified a protein that is able to detect various allergens in the respiratory tract, which are responsible for asthma attacks. This study, co-led by Corinne Cayrol and Jean-Philippe Girard, was published in Nature Immunology on March 19, 2018. It offers hope for breakthroughs...
Thanks to a study conducted in pregnant women and their unborn children during the Zika epidemic in the French territories in the Americas, researchers from Inserm, Institut Pasteur and the University Hospital of Guadeloupe have been able to accurately estimate the risk of severe neurological complications in babies. They have also determined that the first trimester of pregnancy is the period which presents the highest risk. While the overall...
Thanks to work coordinated by Inserm and its researchers at the Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS), French child health and immunization record booklets (carnets de santé) distributed from April 1, 2018 will contain new reference growth curves. These curves were devised according to a totally innovative method in which over 5 million measurements collected from children aged 0 to 18 years were analyzed....
Excessive alcohol consumption is linked to a threefold increase in overall dementia risk and a twofold increase in that of developing Alzheimer’s disease, making it a major modifiable risk factor for these conditions. This is the conclusion of an Inserm study performed in collaboration with Canadian researchers via the QalyDays Study Group . Using exhaustive data on hospitalizations in France between 2008 and 2013, the researchers studied the link...
A new study bringing together researchers from Inserm, Inra and University of Paris 13 (Center of Research in Epidemiology and Statistics Sorbonne Paris Cité, EREN team) suggests a link between the consumption of ultra-processed food and the additional risk of developing cancer. In total, 104,980 participants from the French NutriNet-Santé cohort were included. During the follow-up period (8 years), 2,228 cases of cancer were diagnosed and validated. ...
