A recent study conducted by Inserm researchers within Irset[1] has shown that sustained ibuprofen use in young male athletes induces a hormonal imbalance known as "compensated hypogonadism", usually observed in elderly males. This situation arises due to the negative effects of ibuprofen on testosterone production, and on the production of two other testicular hormones. These results have been published in Proceedings of the National Academy of Sciences.
An international study led by scientists from Inserm and Paris Diderot University (France), the University of Chicago (USA), the National Heart and Lung Institute (UK) and the University of Colorado Anschutz Medical Campus (USA) together with researchers of the Trans-National Asthma Genetics Consortium (TAGC) has discovered five new regions of the genome that increase the risk of asthma. This study is published online in Nature Genetics on 22 December...
A lower risk of type 2 diabetes has been observed among individuals consuming food rich in antioxidants. This effect is largely contributed by fruit, vegetables, tea and other hot beverages, as well as moderate consumption of alcohol, as shown in a recent study from an Inserm research group, published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD)
The French National Institute for Health and Medical Research (Inserm) and the Directorate of Research, Studies, Evaluation and Statistics (DREES) have published the preliminary results of the French National Perinatal Survey 2016. This report, based on a sample of births representing all births in France for the year 2016, presents the changes in the main perinatal indicators of health, medical practices and risk factors. It also describes the organization...
An epidemiological study carried out by Inserm on families from the EDEN cohort (500 boys born between 2003 and 2006 and their mothers) shows that exposure during pregnancy to certain phenols and phthalates is associated with behavioral problems in boys between 3 and 5 years of age. The most worrying compounds in this respect are bisphenol A, triclosan and dibutyl phthalate (DBP).
Between 2010 and 2012, 256 women died in France from causes linked to pregnancy, labor, or following childbirth, amounting to 85 such cases a year. Although inequalities remain, improvements have been observed in the provision of labor care, with the death rate from hemorrhage halving. These epidemiological results have been made public by the triennial report of the Confidential Inquiry into Maternal Deaths (Enquête Confidentielle sur les Morts Maternelles, ENCMM) in...
It’s good news. Over the last 20 years there has been a marked improvement in the survival rate of preterm infants, and rates of brain damage at the age of 2 years have halved. These are the latest results of the EPIPAGE-2 study carried out by researchers from the Inserm group EPOPé - Obstetrical, Perinatal, and Pediatric Epidemiology Team at the Center for Research in Epidemiology and Statistics, Sorbonne...
Scientists from the Institut Pasteur, Inserm, the Collège de France and Pierre & Marie Curie University have recently demonstrated that mutations in three genes responsible for Usher syndrome – a hereditary condition that affects both hearing and sight – influence not only the workings of the ear, specifically the function of sensory cells in the cochlea, but also the development of the auditory cortex. Their discovery could explain why...
Physical activity in adulthood is not associated with a reduced risk of developing dementia. However, a decline in this activity is observed during the decade preceding its diagnosis. If this decline in activity cannot be considered as an early sign of dementia, it could be one sign - among others - to be taken into account by the attending physician. This is demonstrated by a study conducted by an...
Multidisciplinary teams from the AP-HP Paris public hospitals network (SAMU75 emergency response dispatch centers and Hôpital européen Georges-Pompidou), as well as from Inserm, the Université Paris-Descartes, and the Paris BSPP medical emergency service, compared, in the French capital, two strategies of extracorporeal cardiopulmonary resuscitation (ECPR) used in patients suffering refractory cardiac arrest (defined as lack of return of spontaneous circulation after 30 minutes of resuscitation). The results of this study,...
JUMODA, a prospective study sponsored by the Paris public hospitals (AP-HP) and conducted between 2014 and 2015 by teams of researchers and clinicians from Inserm, Université Paris Descartes and AP-HP, has shed new light on the mode of delivering twins. According to the coordinators of JUMODA ("MOde D’Accouchement des JUmeaux"), Professors Thomas Schmitz and François Goffinet, vaginal delivery is associated with decreased neonatal morbidity and mortality rates for both...
