Attribué par la fondation Danoise Lundbeck, le « Brain Prize » est un grand prix international qui récompense des scientifiques pour l’importance de leurs recherches en neurosciences. Il est doté d’un montant d’un million d’euros. Il met cette année à l’honneur des travaux débutés il y a près de quarante ans par quatre scientifiques français sur CADASIL, une maladie cérébrovasculaire héréditaire, qui provoque crises de migraine, accidents vasculaires cérébraux et...
A mechanism of tolerance towards intestinal flora is thought to be implicated in the onset of a rare familial autoinflammatory disease induced by cold temperatures. This is the finding of researchers from the Center for Infection and Immunity of Lille (Inserm/Université de Lille/CNRS/University Hospital Lille/Institut Pasteur de Lille), the Pathophysiology of Pediatric Genetic Diseases laboratory (Inserm/Sorbonne Université) and the Department of Immunology at the University of Hohenheim. Their research,...
Hospital teams Pitié-Salpêtrière Hospital AP-HP, Inserm and the Institute of the brain and spinal cord - AP-HP / CNRS / Inserm / University-Sorbonne showed appreciation caregivers (nurses and nursing auxiliaries) for the state of consciousness of patients represented a real added value to medical and electrophysiological exams and conventional brain imaging diagnostics.
A team Sorbonne / AP-HP / Inserm, led by Professor Irene Netchine, physiology professor at Sorbonne University and pediatrician at the Hospital Armand Trousseau AP-HP, studied the molecular mechanisms of the clinical similarity between syndrome Temple and Russell Silver syndrome. Their study, published in Science Advances , highlights the importance of gene network concept "imprinted" in the diagnosis and treatment of patients with these rare syndromes.
In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness – a hearing disorder that represents one of the most frequent cases of congenital genetic deafness. Individuals with DFNB9 deafness are profoundly deaf as they are deficient...
Teams from the Biological Therapy Department and Pediatric Immunohematology Unit at Necker-Enfants Malades Hospital AP-HP, the Fetal Medicine Department at Trousseau Hospital AP-HP, Inserm, the Imagine Institute, Université Paris Descartes and Sorbonne Université have achieved the in utero transplantation of hematopoietic stem cells in a fetus with X-linked severe combined immunodeficiency.
Inserm was tasked by the French Ministry of Sports with producing a collective expert review in order to take stock of scientific knowledge and to analyze, within the scope of chronic diseases, the impact of physical activity and its place in the care pathway. This review is based on a critical analysis of the international scientific literature made by a multidisciplinary group of thirteen researchers with expertise in various...
A painkiller nanomedicine has just been developed by Patrick Couvreur’s team at Institut Galien Paris-Sud (Université Paris-Sud/CNRS). This new drug specifically targets the area of painful inflammation without causing the addiction phenomena of current medication.
A study published in The Lanceton 11 february 2019shows that direct-acting antivirals have short-term clinical benefits in the treatment of hepatitisCvirusinfection. These results come from ANRS-funded interdisciplinary research conducted byclinicians,hepatologists, and epidemiologistsof theInserm, SorbonneUniversityand AP-HPandcoordinatedby ProfessorsFabrice CarratandStanislas Pol,and Dr Hélène Fontaine,1in9895 patientsof the ANRS CO 22 HEPATHERnational cohortrecruitedin 32 centers in France.
A team of researchers from Inserm, CNRS, Université Grenoble Alpes and Barcelona Institute for Global Health has shown that prenatal and postnatal exposure to various chemical pollutants is linked to decreased respiratory function in children. These results, based on the concept of the exposome (defined as the totality of an individual’s environmental exposures from conception until old age), were obtained as part of the European HELIX project and have...