At the request of the Agence Nationale de Sécurité du Médicament et des produits de santé (ANSM) [French National Agency of Medicine and Health Products Safety], a group of researchers managed by Florent de Vathaire in Inserm Unit 1018 Centre for epidemiology and population health research is launching a study entitled LUCIE.
A new ultrasound imaging technique has provided the first ever in vivo visualization of activity in the piriform cortex of rats during odor perception. This deep-seated brain structure plays an important role in olfaction, and was inaccessible to functional imaging until now. This work also sheds new light on the still poorly known functioning of the olfactory system, and notably how information is processed in the brain.
One of the goals of the laboratory is to develop laser and microfabrication technologies with the aim of printing tissues in vitro and in vivo. The researchers in the laboratory were pioneers in Europe, developing laser-assisted bioprinting from 2005. This Inserm/University of Bordeaux joint research unit is one of a very few worldwide to use this process. The objective of Fabien Guillemot’s team is therefore not only to position...
How many patients receive an incorrect diagnosis of Alzheimer’s disease? The answer is a surprisingly high number: over a third! To reduce the number of errors, the diagnostic criteria must be the most reliable possible, especially at the very early stages of the disease. For the last decade, an international team of neurologists, coordinated by Bruno Dubois (Inserm/Pierre and Marie Curie University/AP-HP Joint Research Unit 975) has been working...
Neurons cannot properly defend themselves against Huntington’s disease, right from the onset of the pathology. This has been discovered by a team of Inserm researchers from the Paris-Seine Biology Institute (IBPS) (Inserm/CNRS/Pierre and Marie Curie University) and their American and Australian colleagues. The cause is the failure of an important mechanism involved in cellular longevity. In addition to this result, the present study shows the importance of restoring the...
Many medical situations require a supply of red blood cells—anaemia, road accidents and chemotherapy, for example. But there is a genuine shortage of blood. Researchers throughout the world are therefore working hard to find solutions to alleviate these shortages, and their sights are set on the potential for creating an unlimited supply of red blood […]
Teams led by Priscille Brodin in Lille and Laurent Marsollier in Angers have studied lesions in patients with Buruli ulcer, a tropical disease.
A l’occasion de leur première grande réunion annuelle, qui a eu lieu ce mardi 17 juin à l’Auditorium de l’Hôpital Européen Georges Pompidou, plusieurs groupes de travail du Comité d’éthique de l’Inserm dont le groupe « Embryon & développement » et le groupe « Genre et recherche en santé » rendent leur avis sous forme de note.
How long does the immune memory response produced by vaccination last? Is it similar to that induced by the infection itself? New information on the A(H1N1) pandemic influenza virus has just been brought to light by researchers at Joint Research Unit 1135, Cimi-Paris (Centre for Immunology and Infectious Diseases - Inserm - Pierre and Marie Curie University).
Scientists from the Institut Pasteur, INSERM, Collège de France, and Pierre and Marie Curie University, in collaboration with a team from the University of Auvergne, identified mice models that mimic high-frequency hearing impairment in humans, with a strong low-frequency sound interference. Their work sheds light on the anomalies causing the hearing impairment and reveals cochlear defects that profoundly affect the way sound frequencies are processed. This work could explain...
Yves Lévy has just been appointed by the Council of Ministers as Chairman and Chief Executive Officer of the French National Institute of Health and Medical Research (Inserm).