- 2021
- Press releases - 09.11.2021
Covid-19 : Le lourd impact de l’épidémie sur la santé mentale des étudiants, notamment pendant les périodes de confinements
La pandémie de Covid-19 s’est accompagnée d’une dégradation de l’état de santé mentale d’une grande partie de la population française. Des chercheurs montrent que les étudiants sont particulièrement vulnérables. Pendant les deux premiers confinements, les prévalences des troubles anxieux et dépressifs, ainsi que des pensées suicidaires, étaient plus élevées dans cette population en comparaison à des non étudiants. Ces résultats, mettent en lumière la nécessité d’une grande vigilance en ce qui concerne la santé mentale des étudiants en contexte épidémique ainsi que l’importance de mettre en place rapidement des interventions spécifiques pour les aider à surmonter les effets délétères de cette crise sanitaire.
- Press releases - 05.11.2021
Cohort study identifies genetic cause for rare form of diet-induced Cushing syndrome
Researchers carried out work, to study the genetic cause of bilateral macronodular adrenal hyperplasia with diet-induced Cushing’s syndrome. This rare disease affects the two adrenal glands located above the kidneys and causes an overproduction of cortisol, a steroid hormone whose excess has harmful consequences for the body . Researchers were able to determine the molecular explanation for the occurrence of this disease 30 years after its initial description.
- Press releases - 04.11.2021
COVID-19: Artificial Intelligence Identifies Gene Signature Specific to Patients Suffering from Critical Forms
What are the molecular and genetic characteristics that distinguish patients with critical forms of COVID-19 – and particularly acute respiratory distress syndrome (ARDS)? Researchers have investigated the biological and genomic data of a targeted cohort of young patients. Patients hospitalized in intensive care with ARDS were compared with COVID-19 patients hospitalized in a non-critical care ward. As part of a Franco-US collaboration, the scientists have succeeded in identifying a gene signature that differentiates these critical patients from their non-critical counterparts.
- Press releases - 03.11.2021
The Utility of a Two-Dose Ebola Vaccine Regimen Confirmed
In response to the 2014-2016 Ebola epidemic, the clinical development of a two-dose regimen of vaccines Ad26.ZEBOV and MVA-BN-Filo was accelerated. Approved in 2020 by the European Commission for use in epidemic emergencies, this regimen continues to demonstrate its relevance. An Inserm study has played a role in evaluating its safety and immunogenicity in healthy adults and in those with HIV and compared different time intervals between the two doses. It has confirmed that this regimen is well tolerated, that the antibodies acquired persist for at least one year, and that they can be easily reactivated by a booster shot.
- Press releases - 28.10.2021
Chatbot for addressing COVID-19 vaccine hesitancy
What if a few minutes of interaction with a chatbot could effectively address vaccine concerns? In an article published in the Journal of Experimental Psychology: Applied (28 October 2021), researchers from the CNRS, INSERM, and ENS-PSL show that such an interface is indeed capable of swaying the vaccine-hesitant.
- Press releases - 21.10.2021
COVID-19: How Does SARS-CoV-2 Infection Affect Vascular Irrigation of the Brain?
A large number of researchers are currently mobilized to increase knowledge of SARS-CoV-2 in order to improve the treatment of infected patients and try to predict the future health impacts of infection with the virus. Researchers have been the first to identify a direct effect of SARS-CoV-2 on the brain’s blood vessels.
- Press releases - 21.10.2021
Découverte de nouveaux marqueurs génétiques à l’origine d’une maladie des artères essentiellement féminine
La dysplasie fibromusculaire artérielle (DFM) est une anomalie de la paroi de certaines artères entraînant une augmentation du risque cardiovasculaire chez les personnes qui en sont atteintes. 3% de la population générale pourrait en être affectée et au moins 80% des personnes atteintes de cette maladie sont des femmes. Des chercheurs sont parvenus à décrire la composante génétique de la maladie, premier par vers l’identification de nouvelles cibles thérapeutiques.
- Press releases - 15.10.2021
Towards the elimination of cholera in Haiti
In 2013, a medical team proposed to the Haitian government and to Unicef a coordinated strategy to fight against cholera, aimed at breaking the chains of transmission. This strategy and its results, which show the apparent cessation of cholera transmission in Haiti since 2019, have just been the subject of a publication in the journal Emerging Infectious Diseases.
- Press releases - 13.10.2021
Study on the role of “ceramides” in infection by SARS-CoV-2 which could constitute a biomarker of severity and a therapeutic target in the management of Covid-19
Teams of researchers published on October 4, 2021 in the journal Molecular Psychiatry (Nature Publishing Group) a summary of the results of the international literature on the central role that “ ceramides ”, a class of lipids, may play a role in SARS-CoV-2 infection.
- Press releases - 12.10.2021
Good tolerance of the BNT162b2 vaccine (Pfizer / BioNTech) and good efficacy of the immune response against SARS-CoV-2 variants in patients with systemic lupus
Teams of researchers measured the antibody and cellular responses generated by a messenger RNA vaccine in patients with systemic lupus (LS). This work shows that vaccination is both well tolerated and effective, even against worrying variants. The factors associated with a poor vaccine response in some of these patients have been identified in order to better anticipate who should benefit from reinforced protective measures and / or adapted vaccine protocols.