Tuesday May 1 is World Asthma Day – a day to educate and raise public awareness to improve the diagnosis and treatment of asthma.
With the genome editing CRISPR-case.9 technique, researchers at INSERM, the hospital Necker Children-AP-HP, and Université Paris Descartes in the Institute Imagine managed to reactivate a gene that may improve the appearance of red blood cells of patients with hemoglobinopathies such as sickle cell anemia and beta-thalassemia. The teams Annarita Miccio, Inserm researcher, Prof. Marina Cavazzana AP-HP and Isabelle André-Schmutz, Inserm researcher show this new avenue of research and treatment of β -hémoglobinopathies in the journal Blood .
To estimate the health of their elderly patients, healthcare professionals have various clinical tools at their disposal: geriatric assessment scales, health questionnaires and frailty scores. However, although these tests are appropriate to a medical context, they are more difficult for primary care physicians (PCPs) to implement because they require time and equipment that they do not necessarily possess. When evaluating the general health of an elderly patient, the PCP will first go on their detailed knowledge of him or her as well as the various signs observed during the consultation (physical appearance, gait, etc.).
Caused by a parasite of the genus Plasmodium, malaria is transmitted to humans through bites from the female Anopheles mosquito. It can also be transmitted via blood transfusion or from mother to child at the end of pregnancy. 
In 2016, the number of deaths caused by malaria was estimated at 445,000. Half of the world’s population is exposed to the risk of developing this disease , hence the need to act.