Monthly Archives: September 2018

Friday 28 September 2018

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20% of reactions to radiologic contrast media are real allergies

A team of Pole-Imaging Research Explorations-European Hospital Georges Pompidou AP-HP, Paris Descartes University and INSERM led by Professor Olivier Clément, and a team from Caen University Hospital and the University of Caen Normandy, led by Dr Dominique Laroche, conducted the first national prospective multicenter study on allergic reactions to contrast media in radiology. 31 centers in France bringing together radiologists investigators, allergists, anesthetists and biologists have investigated 245 cases of hypersensitivity to contrast media.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology, Circulation, metabolism, nutrition, Health technologies | Tagged | Comments closed

A molecule could relieve patients suffering from chronic diarrhea with familial amyloid neuropathy

The teams of hepato-gastroenterology department of adult Bicetre Hospital, AP-HP, in collaboration with the department of neurology adult, Inserm and the Université Paris-Sud, show that a derivative of somatostatin may be effective to treat chronic diarrhea suffered by patients with family amyloid neuropathy (NAF). This side effect concerns a quarter of patients after 5 years of follow-impairing their quality of life.

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Tuesday 27 September 2018

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Wednesday 26 September 2018

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Tuesday 25 September 2018

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Deciphering the link between skin allergies and the gut microbiota

Over the last few years, scientists have discovered connections between gut microbiota imbalances and various diseases. Now, in a study using mice, biologists from the CNRS, INSERM, and Claude Bernard Lyon 1 University—together with colleagues from the Institut Pasteur de Lille and the NIH (USA)—have revealed a surprising relationship between a viral detection system, the composition of the gut microbiota, and the development of skin allergies.[1] Their findings, published in PNAS (September 24, 2018) suggest potential new therapies.

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Liver Cancer: When the Cell Environment Plays a Role in Tumor Development

Liver cancer is the second most deadly form of cancer worldwide. While the majority of patients develop hepatocellular carcinoma, 10 to 20 % develop the second type of primary liver cancer: intrahepatic cholangiocellular carcinoma – a highly-invasive cancer of the liver bile ducts. And while both these tumor types have some risk factors in common, the number of patients presenting with intrahepatic cholangiocellular carcinoma has seen a marked increase in recent years. A team of researchers led by Prof. Lars Zender from University Hospital Tübingen (Germany), in conjunction with researchers from the National Cancer Institute (Bethesda, United States), Institut Pasteur, Inserm and CNRS, has recently demonstrated that the cell environment, with its dying liver cells, determines the path taken by the tumor cells. These findings were published in Nature on September 12, 2018.

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Monday 21 September 2018

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Major advances in the diagnosis and treatment of allograft rejection

Prof. Alexander Loupy, Hospital Necker Children AP-HP and Prof. Carmen Lefaucheur, the Saint-Louis Hospital AP-HP and the University Paris Diderot in the Cardiovascular Research Center (Inserm / Paris Descartes University), showed, in an article published in the journal   New England Journal of Medicine September 20, 2018, the latest advances and applications of artificial intelligence carried out in the field of transplantation, including the diagnosis and the treatment of allograft rejection.

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